Description

(3α,14S,16α)-14,15-Dihydro-14-Hydroxy-20-Oxoeburnamenine-14-Carboxylic Acid Methyl Ester is a high-purity, structurally defined alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and reference standard for the production and analysis of complex therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and the development of analytical methods.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in analytical laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and metabolic pathways.
• Process Chemistry: Serves as a starting material or intermediate in process development and scale-up activities within fine chemical production.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and the development of new catalytic methodologies.

Basic Information

Product Name	(3α,14S,16α)-14,15-Dihydro-14-Hydroxy-20-Oxoeburnamenine-14-Carboxylic Acid Methyl Ester
CAS No.	6880-35-9
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-20-oxo-, methyl ester, (3α,14β,16α)-; Methyl (3α,14β,16α)-14,15-dihydro-14-hydroxy-20-oxoeburnamenine-14-carboxylate; Vincamine derivative; Apovincaminic acid methyl ester derivative; 14-Hydroxyeburnamenine-14-carboxylic acid methyl ester; 20-Oxoeburnamenine-14-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (3α,14S,16α)-14,15-Dihydro-14-Hydroxy-20-Oxoeburnamenine-14-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.