Description

(3R)-4,4Aα-Dihydro-3α,7,8-Trimethoxy-3H,6H-5β,10Bβ-Ethanophenanthridin-9-Ol CAS NO 6874-70-0 is a high-purity, complex alkaloid derivative characterized by its specific stereochemistry and functional groups. This compound matters as a critical advanced pharmaceutical intermediate and a valuable scaffold for medicinal chemistry research, enabling the synthesis of novel therapeutic agents. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential alkaloid-based therapeutics.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Used as an analytical standard in quality control and method development for related compounds.
• Biochemical Research: Investigated for its biological activity and potential interactions with various enzyme systems.
• Process Development: Employed in scaling up synthetic routes for complex natural product analogs.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis and natural product chemistry.

Basic Information

Product Name	(3R)-4,4Aα-Dihydro-3α,7,8-Trimethoxy-3H,6H-5β,10Bβ-Ethanophenanthridin-9-Ol
CAS No.	6874-70-0
Molecular Formula	C19H25NO4
Molecular Weight	331.41 g/mol
Synonyms	9-Phenanthridinol, 1,2,3,4,4a,5,6,10b-octahydro-3,7,8-trimethoxy-4a-methyl-, (3R,4aR,5R,10bR)-; (3R,4aR,5R,10bR)-3,7,8-Trimethoxy-4a-methyl-1,2,3,4,4a,5,6,10b-octahydro-9-phenanthridinol; NSC 169864; Alkaloid C-3; Aporphine alkaloid derivative
EINECS	Contact for details

Quality Control

Our (3R)-4,4Aα-Dihydro-3α,7,8-Trimethoxy-3H,6H-5β,10Bβ-Ethanophenanthridin-9-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.