Description

5-Amino-2-Methylene-1,3,3-Trimethylindoline is a versatile indoline derivative, a key heterocyclic building block prized for its unique structural framework. Its primary value lies in serving as a crucial intermediate in the synthesis of complex organic molecules, particularly functional dyes and advanced pharmaceutical compounds. This product is essential for research and development chemists, process engineers, and manufacturers in the fine chemicals, specialty dyes, and advanced material sectors.

Application

• Dye and Pigment Intermediate: A critical precursor in the synthesis of advanced methine dyes, cyanine dyes, and other specialty colorants for imaging, textiles, and electronics.
• Pharmaceutical Synthesis: Serves as a key building block for constructing indoline-based pharmacophores in medicinal chemistry research and active pharmaceutical ingredient (API) development.
• Organic Light-Emitting Diodes (OLEDs): Used in the development of novel organic semiconductor materials and emissive layers due to its electron-donating properties and rigid structure.
• Photographic Sensitizers: Employed in the manufacture of spectral sensitizers for silver halide photographic materials.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new heterocyclic chemistry, polymerization initiators, and ligand systems.
• Fine Chemical Synthesis: Utilized as a versatile intermediate for creating complex molecules with applications in agrochemicals and functional materials.

Basic Information

Product Name	5-Amino-2-Methylene-1,3,3-Trimethylindoline
CAS No.	6872-05-5
Molecular Formula	C12H16N2
Molecular Weight	188.27 g/mol
Synonyms	5-Amino-2-methylene-1,3,3-trimethylindoline; 2-Methylene-1,3,3-trimethyl-5-aminoindoline; 5-Amino-2,3,3-trimethyl-3H-indole; 5-Amino-1,3,3-trimethyl-2-methyleneindoline; 1,3,3-Trimethyl-2-methylene-5-aminoindoline; Fischer's Base, 5-Amino-; 5-Aminofischer base; 5-Amino-2-methylene-1,3,3-trimethyl-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Methylene-1,3,3-Trimethylindoline is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable supply to demanding industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.