Description

Imidazole-D3 is a deuterated isotopologue of the fundamental heterocyclic compound imidazole, where three hydrogen atoms are replaced by deuterium. This stable isotope-labeled compound is essential for applications requiring precise molecular tracking and analysis without interfering with the chemical's inherent biological or catalytic activity. It is a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity internal standards for mass spectrometry and NMR spectroscopy.

Application

• Pharmaceutical Research & Development: Serves as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantitative analysis of drugs and metabolites.
• Metabolomics and Proteomics: Used in stable isotope labeling for tracking metabolic pathways and protein interactions in complex biological systems.
• Agrochemical Analysis: Employed in the development and residue testing of pesticides and herbicides, ensuring accurate environmental and food safety monitoring.
• Catalysis Studies: Acts as a mechanistic probe in catalytic reactions involving imidazole-based systems, such as in organometallic chemistry and enzyme model studies.
• NMR Spectroscopy Solvent & Reagent: Utilized as a deuterated solvent shift reagent or a labeled precursor in synthetic chemistry to simplify spectral interpretation.
• Quality Control & Reference Standard: Provides a certified reference material for calibrating analytical instruments and validating methods in quality control laboratories.

Basic Information

Product Name	Imidazole-D3
CAS No.	6745-43-3
Molecular Formula	C3D3N2H2
Molecular Weight	71.10 g/mol
Synonyms	1,3-Dideutero-2,4,5-trideuteroimidazole; 1H-Imidazole-2,4,5-d3; Deuterated Imidazole; Imidazole-d3; Imidazole-2,4,5-d3; 1,3-Dideuteroimidazole-2,4,5-d3; 2,4,5-Trideutero-1H-imidazole
EINECS	Contact for details

Quality Control

Our Imidazole-D3 is manufactured under strict quality management systems to ensure exceptional isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity by HPLC, and residual solvent content. We adhere to relevant standards for high-purity reference materials, ensuring reliability for your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (D-atom %)	≥ 98%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.