Description

(2R,11R)-3-Allyl-6-Ethyl-1,2,3,4,5,6-Hexahydro-11-Methyl-2α,6α-Methano-3-Benzazocin-8-Ol is a complex, stereochemically defined benzazocine derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its intricate methano-bridged structure makes it a valuable chiral building block and a potential intermediate for developing novel pharmacologically active compounds. This high-purity chemical is essential for researchers and manufacturers in medicinal chemistry, process development, and fine chemical synthesis who require reliable, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed in advanced organic synthesis due to its defined stereocenters, facilitating the construction of complex, enantiomerically pure molecules.
• Reference Standard: Utilized as an analytical standard for quality control and method development in laboratories characterizing related compounds.
• Process Chemistry Development: Acts as an intermediate in the scale-up and optimization of synthetic routes for target active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Supports chemical and pharmacological studies in universities and research institutes focusing on heterocyclic and alkaloid chemistry.

Basic Information

Product Name	(2R,11R)-3-Allyl-6-Ethyl-1,2,3,4,5,6-Hexahydro-11-Methyl-2α,6α-Methano-3-Benzazocin-8-Ol
CAS No.	6654-31-5
Molecular Formula	C19H27NO
Molecular Weight	285.43 g/mol
Synonyms	8-Hydroxy-3-allyl-6-ethyl-11-methyl-2,6-methano-3-benzazocine; 3-Allyl-6-ethyl-1,2,3,4,5,6-hexahydro-11-methyl-2,6-methano-3-benzazocin-8-ol; (-)-8-Hydroxy-3-allyl-6-ethyl-11-methyl-2,6-methano-3-benzazocine; (2R,11R)-(-)-8-Hydroxy-3-allyl-6-ethyl-11-methyl-2,6-methano-3-benzazocine; Benzazocine derivative 6654-31-5; Potential opioid ligand intermediate.
EINECS	Contact for details

Quality Control

Our (2R,11R)-3-Allyl-6-Ethyl-1,2,3,4,5,6-Hexahydro-11-Methyl-2α,6α-Methano-3-Benzazocin-8-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including chiral purity verification, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.