Description

1-(2-Chlorophenyl)-2,2-Dimethyl-Propan-1-Ol is a versatile organic building block characterized by its chlorinated phenyl and tertiary alcohol functional groups. This compound is valued for its role as a key chiral intermediate in the synthesis of complex molecules, offering significant utility in advanced chemical manufacturing. It is primarily sought after by research institutions and industrial producers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where its structural motif contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Material Science Research: Acts as a monomer or modifying agent in the development of novel polymers with tailored properties.
• Academic & R&D: Utilized in organic chemistry research for method development and the exploration of new synthetic pathways.

Basic Information

Product Name	1-(2-Chlorophenyl)-2,2-Dimethyl-Propan-1-Ol
CAS No.	6642-36-0
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	2-Chloro-α,α-dimethylbenzenemethanol; (2-Chlorophenyl)neopentyl alcohol; 1-(2-Chlorophenyl)-2,2-dimethyl-1-propanol; 2-Chloro-α,α-dimethylbenzyl Alcohol; α-(2-Chlorophenyl)-neopentyl alcohol; Neopentyl(2-chlorophenyl)carbinol; 2-Chloro-α,α-dimethylbenzyl Alcohol
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-2,2-Dimethyl-Propan-1-Ol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by IR and NMR, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as required)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.