Description

5-Nitro-1H-Indole-3-Carbaldehyde is a versatile and high-value nitro-substituted indole derivative, serving as a critical synthetic building block in advanced organic chemistry. Its unique structure, featuring both an aldehyde and a nitro group on the indole scaffold, makes it an indispensable precursor for constructing complex heterocyclic compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the creation of organic semiconductors, dyes, and photoactive materials due to its electron-withdrawing nitro group.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent tags and molecular probes for biochemical assays.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Nitro-1H-Indole-3-Carbaldehyde
CAS No.	6625-96-3
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	5-Nitroindole-3-carboxaldehyde; 3-Formyl-5-nitroindole; 5-Nitro-1H-indole-3-carboxaldehyde; 5-Nitroindole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 5-nitro-; 5-Nitro-3-indolecarboxaldehyde; 5-Nitro-3-formylindole; 5-Nitroindole-3-aldehyde
EINECS	229-593-5

Quality Control

Every batch of 5-Nitro-1H-Indole-3-Carbaldehyde is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality system is designed to support cGMP-compliant development and production workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.