Description

1,2,3,4-Tetrahydroisoquinoline-1-Thione is a versatile heterocyclic organic compound featuring a thione functional group, making it a valuable synthon in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex nitrogen- and sulfur-containing molecular architectures. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides due to its bioactive scaffold.
• Organic Synthesis Building Block: Employed in heterocyclic chemistry for constructing complex molecules like alkaloids and other fused ring systems.
• Material Science Research: Investigated as a monomer or ligand precursor for advanced polymers and coordination complexes.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinoline-1-Thione
CAS No.	6552-60-9
Molecular Formula	C9H9NS
Molecular Weight	163.24 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-isoquinolinethione; 1-Thioxo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-1-thiol (tautomer); 1(2H)-Isoquinolinethione, 3,4-dihydro-; THIQ-1-thione; 1-Thioxotetrahydroisoquinoline; 1-Mercaptotetrahydroisoquinoline (tautomeric form); 1-Isoquinolinethione, 3,4-dihydro-
EINECS	229-479-9

Quality Control

Our 1,2,3,4-Tetrahydroisoquinoline-1-Thione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and other relevant methods. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.