Description

Triisopropylsilane is a versatile organosilicon compound, widely recognized for its utility as a mild reducing agent and a versatile protecting group reagent in complex organic synthesis. Its value lies in its selective reactivity and ability to function under conditions compatible with sensitive functional groups, making it indispensable for high-value chemical manufacturing. This product is essential for research and production teams in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent in the production of active pharmaceutical ingredients (APIs), particularly for the reduction of sensitive functional groups.
• Peptide and Oligonucleotide Chemistry: Serves as an effective protecting group for hydroxyl and carboxyl functions during solid-phase and solution-phase synthesis.
• Agrochemical Manufacturing: Employed in the synthesis of complex pesticide and herbicide molecules requiring selective reduction steps.
• Material Science & Surface Modification: Acts as a precursor or silylating agent for modifying surface properties of silica, glass, and other inorganic materials.
• Cross-Coupling Reactions: Functions as a mild hydride source in palladium-catalyzed reactions, such as reductive dehalogenations.
• Fine Chemical Production: Utilized in the multistep synthesis of flavors, fragrances, and other specialty organic compounds.

Basic Information

Product Name	Triisopropylsilane
CAS No.	6485-79-6
Molecular Formula	C9H22Si
Molecular Weight	158.35 g/mol
Synonyms	Triisopropylsilane; TIPS; Triisopropylsilyl hydride; Triisopropylsilicon hydride; 1,1',1''-(Silylidyne)trispropane; Tri-iso-propylsilane; Triisopropyl monosilane; (i-Pr)3SiH
EINECS	229-355-8

Quality Control

Our Triisopropylsilane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including gas chromatography (GC) and NMR, to meet stringent specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.428 - 1.432
Density (20°C)	0.780 - 0.790 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.