Description

1-Chloro-3-Mercapto-2-Propanol is a versatile organosulfur compound featuring both a chloro and a thiol functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing a wide range of specialty chemicals, including pharmaceuticals, agrochemicals, and polymer additives. It is particularly sought after by R&D chemists and process engineers in the fine chemical, pharmaceutical, and material science industries for its reactivity and utility in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfur or requiring specific chiral centers.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive sites for molecular diversification.
• Polymer Modification & Cross-linking Agent: Serves as a monomer or cross-linker in the production of specialty polymers, resins, and adhesives, imparting specific properties like flexibility or chemical resistance.
• Chemical Intermediate for Fine Chemicals: Employed in the synthesis of complex ligands, catalysts, and other high-value specialty chemicals used in research and manufacturing.
• Bioconjugation & Protein Chemistry: The thiol group is reactive towards maleimides and other electrophiles, making it useful in bioconjugation techniques and modifying biomolecules.

Basic Information

Product Name	1-Chloro-3-Mercapto-2-Propanol
CAS No.	6478-04-2
Molecular Formula	C3H7ClOS
Molecular Weight	126.60 g/mol
Synonyms	3-Chloro-2-hydroxy-1-propanethiol; 1-Chloro-3-mercaptopropan-2-ol; 3-Chloro-2-hydroxypropyl mercaptan; 2-Hydroxy-3-chloropropyl mercaptan; 3-Chloro-1-mercapto-2-propanol; Glycerol α-chlorohydrin β-thioglycerol; Thioglycerol chlorohydrin
EINECS	229-329-6

Quality Control

Our 1-Chloro-3-Mercapto-2-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including assay (HPLC/GC), identity confirmation (IR), and impurity profiling, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its properties of being easily oxidized and light-sensitive, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.510 - 1.520
Density (g/mL, 20°C)	1.25 - 1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.