Description

(1-Phenyl-1H-Benzoimidazol-2-Yl)-Acetonitrile is a versatile and high-value organic intermediate characterized by its fused benzimidazole-phenyl core functionalized with an acetonitrile group. This compound matters for its role as a critical building block in the synthesis of complex heterocyclic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition, antiviral activity, or other biological pathways where the benzimidazole scaffold is privileged.
• Agrochemical Synthesis: Used in the development of new-generation fungicides, herbicides, and plant growth regulators that require the benzimidazole pharmacophore.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), or advanced polymers.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags, enzyme inhibitors, or other molecular probes for diagnostic and research applications.
• Catalyst Ligand Development: The nitrogen-rich structure makes it a candidate for developing novel ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	(1-Phenyl-1H-Benzoimidazol-2-Yl)-Acetonitrile
CAS No.	6468-35-5
Molecular Formula	C15H11N3
Molecular Weight	233.27 g/mol
Synonyms	2-(1-Phenyl-1H-benzimidazol-2-yl)acetonitrile; (1-Phenyl-1H-benzimidazol-2-yl)acetonitrile; 2-(1-Phenylbenzimidazol-2-yl)acetonitrile; 1-Phenyl-1H-benzimidazole-2-acetonitrile; 2-Cyanomethyl-1-phenylbenzimidazole; 1-Phenyl-2-cyanomethylbenzimidazole; α-(1-Phenyl-1H-benzimidazol-2-yl)acetonitrile; Benzimidazole, 2-(cyanomethyl)-1-phenyl-
EINECS	Contact for details

Quality Control

Our (1-Phenyl-1H-Benzoimidazol-2-Yl)-Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.