Description

3-Oxo-2,3-Dihydrobenzo[B]Thiophene-2-Carboxylic Acid is a versatile heterocyclic carboxylic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique benzo[b]thiophene scaffold makes it a valuable building block for constructing complex molecular architectures with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich fused ring system.
• Ligand and Catalyst Development: Serves as a starting point for synthesizing specialized chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Chemistry: Intermediate for creating specialized chromophores and fluorophores used in imaging, sensors, and high-performance pigments.
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis, including cyclization reactions and heterocycle functionalization.

Basic Information

Product Name	3-Oxo-2,3-Dihydrobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	6421-82-5
Molecular Formula	C9H6O3S
Molecular Weight	194.21 g/mol
Synonyms	2-Carboxy-3-oxo-2,3-dihydrobenzo[b]thiophene; 2,3-Dihydro-3-oxobenzo[b]thiophene-2-carboxylic Acid; 2-Carboxybenzo[b]thiophen-3(2H)-one; 3-Oxo-2,3-dihydro-1-benzothiophene-2-carboxylic Acid; 2-Benzothiophenecarboxylic acid, 2,3-dihydro-3-oxo-; 2,3-Dihydro-3-oxo-1-benzothiophene-2-carboxylic Acid; 3-Oxo-2,3-dihydrobenzo[b]thiophene-2-carboxylic acid (principal IUPAC name)
EINECS	229-190-7

Quality Control

Our production of 3-Oxo-2,3-Dihydrobenzo[B]Thiophene-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.