Description

5-Bromo-1,2-dihydro-indol-3-one is a versatile brominated indolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it a valuable building block for constructing complex heterocyclic frameworks, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photochromic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the bromo-indolinone moiety into more complex molecules.
• Biochemical Tool Compound: Used in research to study enzyme mechanisms and as a scaffold for probe development in chemical biology.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic routes in university and industrial research laboratories.

Basic Information

Product Name	5-Bromo-1,2-dihydro-indol-3-one
CAS No.	6402-02-4
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	5-Bromoindolin-3-one; 5-Bromo-1,2-dihydro-3H-indol-3-one; 5-Bromo-3-indolinone; 3-Indolinone, 5-bromo-1,2-dihydro-; 5-Bromooxindole; 5-Bromo-2,3-dihydro-1H-indol-3-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2-dihydro-indol-3-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.