Description

4-Chloroisatin is a versatile halogenated isatin derivative, a key heterocyclic building block in advanced organic synthesis. Its value lies in its reactive carbonyl and chloro-substituted aromatic ring, which enables precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Core scaffold for synthesizing kinase inhibitors, anticancer agents, and other bioactive molecules.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Precursor: Used in the synthesis of specialized indole-based dyes and colorants.
• Material Science Research: Monomer or precursor for functional polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the development of enzyme inhibitors and molecular probes for biochemical research.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	4-Chloroisatin
CAS No.	6344-05-4
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	4-Chloro-1H-indole-2,3-dione; 4-Chloro-2,3-dioxoindoline; 4-Chloroindole-2,3-dione; 4-Chloroisatin; 4-Chlorooxindole; 4-Cl-Isatin; 4-Chloro-1H-indole-2,3-dione; 4-Chloroindoline-2,3-dione
EINECS	228-754-4

Quality Control

Our 4-Chloroisatin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	248 - 252 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.