Description

2-Acetyl-5-Chlorothiophene is a versatile heterocyclic building block characterized by its acetyl and chloro substituents on the thiophene ring. This compound is highly valued in organic synthesis for its reactivity, serving as a key intermediate in the development of more complex molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for biological activity.
• Material Science Research: Serves as a monomer or building block for developing conductive polymers, organic semiconductors, and specialty dyes.
• Organic Synthesis: Employed in various name reactions for constructing complex heterocycles, including Suzuki couplings and cyclocondensations.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new chemical entities.

Basic Information

Product Name	2-Acetyl-5-Chlorothiophene
CAS No.	6310-09-4
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	1-(5-Chloro-2-thienyl)ethanone; 5-Chloro-2-acetylthiophene; 5-Chloro-2-thienyl methyl ketone; 2-Thienyl, 5-chloro-, methyl ketone; 2-Acetyl-5-chlorothiophene; Methyl 5-chloro-2-thienyl ketone; 1-(5-Chlorothiophen-2-yl)ethan-1-one
EINECS	228-638-5

Quality Control

Our 2-Acetyl-5-Chlorothiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.