Description

4-Pyridineethanethiol Hydrochloride is a versatile sulfur-containing heterocyclic building block and a key intermediate in organic synthesis. Its value lies in its dual functionality, featuring both a reactive thiol group and a pyridine moiety, which makes it essential for constructing complex molecular architectures. This compound is particularly sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for applications such as drug discovery, ligand synthesis, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Ligand Synthesis for Catalysis: Used to prepare specialized ligands for transition metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with novel modes of action.
• Bioconjugation Chemistry: The thiol group enables site-specific modification of proteins, peptides, and other biomolecules for diagnostic and therapeutic applications.
• Material Science: Employed in the synthesis of functionalized polymers and surface modifiers with specific chemical properties.
• Chemical Biology Probes: Used to create molecular probes for studying enzyme function and cellular processes.

Basic Information

Product Name	4-Pyridineethanethiol Hydrochloride
CAS No.	6298-11-9
Molecular Formula	C7H9NS•HCl
Molecular Weight	175.67 g/mol
Synonyms	2-(4-Pyridyl)ethanethiol Hydrochloride; 4-(2-Mercaptoethyl)pyridine Hydrochloride; 4-Pyridylethanethiol Hydrochloride; 2-(Pyridin-4-yl)ethan-1-thiol Hydrochloride; 4-Pyridinethiol, 2-ethyl-, hydrochloride; 4-PET•HCl
EINECS	Contact for details

Quality Control

Our 4-Pyridineethanethiol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and research environments where traceability and reliability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.