Description

Ethyl 2-Cyano-3-(1H-Indol-3-Yl)Acrylate is a versatile indole-based acrylate derivative that serves as a crucial synthetic intermediate. This compound is valued for its unique molecular structure, which enables the construction of complex heterocyclic frameworks and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and plant growth regulators that leverage the indole scaffold.
• Organic Synthesis: Serves as a Michael acceptor and a dipolarophile in cycloaddition reactions for constructing complex heterocycles.
• Material Science: Investigated as a precursor for organic semiconductors, nonlinear optical (NLO) materials, and photoactive polymers.
• Bioconjugation Chemistry: Utilized in developing fluorescent probes and bioconjugation linkers due to its reactive acrylate and cyano groups.
• Academic & R&D: Essential reagent in university and corporate research laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	Ethyl 2-Cyano-3-(1H-Indol-3-Yl)Acrylate
CAS No.	6286-56-2
Molecular Formula	C₁₄H₁₂N₂O₂
Molecular Weight	240.26 g/mol
Synonyms	Ethyl (2E)-2-Cyano-3-(1H-indol-3-yl)acrylate; Ethyl (E)-2-Cyano-3-indol-3-ylacrylate; 2-Propenoic acid, 2-cyano-3-(1H-indol-3-yl)-, ethyl ester; 3-Indolylacrylic acid ethyl ester, 2-cyano-; Ethyl 2-Cyano-3-indol-3-ylacrylate; (E)-Ethyl 2-cyano-3-(1H-indol-3-yl)acrylate; Ethyl α-Cyano-β-(3-indolyl)acrylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyano-3-(1H-Indol-3-Yl)Acrylate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.