Description

3-(2-Morpholinoethyl)Morphine Monohydrate is a specialized morphine derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its potential as a key intermediate or reference standard in the synthesis and study of novel opioid receptor ligands. It serves critical needs for research institutions, pharmaceutical companies, and analytical laboratories engaged in neuropharmacology, medicinal chemistry, and controlled substance analysis. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Pharmaceutical R&D Intermediate: Serves as a crucial building block in the synthesis of novel analgesic compounds and opioid receptor modulators.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in forensic and pharmaceutical laboratories.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to understand the impact of morpholinoethyl substitution on opioid pharmacology.
• Biochemical Research: Utilized in in vitro assays to investigate binding affinity and functional activity at mu, delta, and kappa opioid receptors.
• Metabolite Synthesis: Acts as a precursor or analog in the synthesis of potential drug metabolites for identification and toxicological studies.

Basic Information

Product Name	3-(2-Morpholinoethyl)Morphine Monohydrate
CAS No.	6254-99-5
Molecular Formula	C25H34N2O5 • H2O
Molecular Weight	460.56 g/mol (Monohydrate)
Synonyms	3-(2-Morpholin-4-ylethyl)morphine monohydrate; Morphine, 3-[2-(4-morpholinyl)ethyl]-, monohydrate; 3-(N-Morpholinoethyl)morphine hydrate; 2-Morpholinoethylmorphine; 3-(2-Morpholinoethyl)morphine hydrate
EINECS	Contact for details

Quality Control

Our 3-(2-Morpholinoethyl)Morphine Monohydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	3.5% - 4.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.