Description

3-Bromo-3-Methyl-But-1-Yne is a versatile halogenated alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a bromine atom and a terminal alkyne group, makes it a valuable precursor for constructing complex molecular architectures through cross-coupling and cycloaddition reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those requiring alkyne functionalization for click chemistry or as a handle for further derivatization.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its bromine moiety allows for efficient introduction into heterocyclic systems.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers and dendrimers with tailored thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligand frameworks for transition metal catalysis.
• Organic Synthesis Building Block: Utilized in Sonogashira coupling, Huisgen cycloaddition, and other C-C bond-forming reactions to create complex organic molecules.
• Chemical Research: A fundamental reagent in academic and industrial R&D laboratories for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	3-Bromo-3-Methyl-But-1-Yne
CAS No.	6214-31-9
Molecular Formula	C5H7Br
Molecular Weight	147.01 g/mol
Synonyms	3-Methyl-3-bromo-1-butyne; 3-Bromo-3-methyl-1-butyne; 1-Bromo-3-methylbut-1-en-3-yne; tert-Butylbromoacetylene; 3-Bromo-3-methylbutyne; Bromotertbutylacetylene
EINECS	Contact for details

Quality Control

Our 3-Bromo-3-Methyl-But-1-Yne is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.