Description

Morphine Sulfate is the sulfate salt of morphine, a principal alkaloid of the opium poppy and a potent opioid analgesic. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of effective pain management medications, offering reliable and consistent therapeutic action. It is essential for pharmaceutical manufacturers, research institutions, and compounding pharmacies developing controlled analgesic products for severe pain relief.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of prescription analgesic tablets, injectable solutions, and oral suspensions for the management of moderate to severe acute and chronic pain.
• Hospital & Clinical Formulations: Used in hospital settings for compounding patient-specific dosages, including controlled-release formulations and solutions for infusion pumps.
• Analgesic Research & Development: Serves as a key reference standard and starting material in pharmacological research for studying opioid receptors and developing new pain therapeutics.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for the relief of severe pain in animals under professional supervision.
• Palliative Care Medications: A cornerstone component in formulations designed for palliative care and cancer pain management protocols.

Basic Information

Product Name	Morphine Sulfate
CAS No.	6211-15-0
Molecular Formula	C17H19NO3 · H2SO4 · 5H2O (pentahydrate)
Molecular Weight	758.83 g/mol (pentahydrate)
Synonyms	Morphine Sulphate; Morphine Sulfate Pentahydrate; Morphine Hydrogen Sulfate; (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate; Morphii sulfas; Morfina sulfato; Morphine, sulfate (2:1), pentahydrate
EINECS	228-278-8

Quality Control

Our Morphine Sulfate is manufactured and tested under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Production adheres to current Good Manufacturing Practices (cGMP) and is compliant with major pharmacopoeial standards, including USP and EP monographs. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation and ensure stability.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder or small colorless crystals
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% solution)	4.0 - 6.0
Specific Rotation	-107° to -109° (c = 2 in water)
Loss on Drying	10.0% - 13.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.