Description

Tri-n-Butyltin Deuteride is a deuterated organotin compound where the hydrogen atom in the tributyltin hydride (TBTH) is replaced by deuterium. This substitution is critical for applications requiring isotopic labeling, particularly in mechanistic studies and spectroscopic analysis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Isotopic Labeling Agent: Used as a deuterium source in organic synthesis for the preparation of deuterium-labeled compounds for metabolic and pharmacokinetic studies.
• Mechanistic Probe: Employed in reaction mechanism elucidation, leveraging the kinetic isotope effect (KIE) to study radical pathways and hydrogen/deuterium transfer reactions.
• Deuterium Reduction: Functions as a selective deuterating agent for the reduction of organic halides, aldehydes, ketones, and other functional groups to introduce deuterium atoms.
• NMR Spectroscopy: Serves as a valuable tool in Nuclear Magnetic Resonance (NMR) spectroscopy to simplify spectra and trace reaction pathways.
• Polymer Chemistry: Used in the synthesis and modification of polymers where deuterium incorporation is needed for structural analysis using techniques like Small-Angle Neutron Scattering (SANS).
• Catalyst and Reagent Research: Applied in the development and testing of new catalysts, particularly in tin-hydride mediated transformations, to understand deuterium transfer efficiency.

Basic Information

Product Name	Tri-n-Butyltin Deuteride
CAS No.	6180-99-0
Molecular Formula	C12H27DSn
Molecular Weight	262.06 g/mol (approx.)
Synonyms	Tributyltin Deuteride; Deuterated Tributyltin Hydride; Tri-n-butylstannane-d; SnD(C4H9)3; TBTH-d; Deuterotributylstannane; (Deuterio)tributylstannane; Tributyl(deuterio)stannane
EINECS	Contact for details

Quality Control

Our Tri-n-Butyltin Deuteride is produced and handled under strict quality protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by NMR (¹H, ²H, ¹³C) and GC-MS to confirm deuterium incorporation and chemical purity. Certificates of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and moisture, it is recommended to handle and store the material under anhydrous conditions. Typical storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Deuterium Content (NMR)	≥ 98 atom % D
Related Substances (GC)	≤ 2.0% (Total)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.