Description

(R)-(+)-n-(1-Phenylethyl)Maleimide is a high-purity, chiral maleimide derivative characterized by its (R)-configuration at the stereogenic center. This compound serves as a critical chiral building block and Michael acceptor in advanced organic synthesis, enabling the stereoselective construction of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), chiral catalysts, and specialty polymers.

Application

• Chiral Auxiliary and Ligand Synthesis: Used as a precursor for synthesizing chiral ligands for asymmetric catalysis.
• Pharmaceutical Intermediate: A key building block in the research and development of enantiomerically pure drugs and bioactive molecules.
• Polymer Modification: Employed as a functional monomer for introducing chiral centers or reactive maleimide groups into polymers and dendrimers.
• Bioconjugation Chemistry: Acts as a Michael acceptor for the selective modification of thiol-containing biomolecules like peptides and proteins.
• Material Science Research: Used in the creation of advanced functional materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(R)-(+)-n-(1-Phenylethyl)Maleimide
CAS No.	6129-15-3
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	(R)-(+)-1-Phenylethylmaleimide; (R)-N-(1-Phenylethyl)maleimide; (R)-N-(α-Methylbenzyl)maleimide; (R)-N-(1-Phenylethyl)-2,5-dihydro-2,5-dioxo-1H-pyrrole; (R)-N-(α-Phenylethyl)maleimide; (R)-N-(1-Phenylethyl)-1H-pyrrole-2,5-dione; (R)-(+)-N-(α-Methylbenzyl)maleimide; Maleimide, N-[(1R)-1-phenylethyl]-
EINECS	Contact for details

Quality Control

Our (R)-(+)-n-(1-Phenylethyl)Maleimide is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profile. We adhere to cGMP principles where applicable to support our clients in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.