Description

(4-Chloro-5-Nitro-2-Pyrimidinylamino)Dichlorophosphine Oxide is a specialized organophosphorus compound featuring a reactive pyrimidine scaffold. This chemical matters as a high-value advanced intermediate for synthesizing complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on nucleoside analogs, kinase inhibitors, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that target specific enzymatic pathways.
• Chemical Biology Probe Development: Serves as a precursor for creating activity-based probes to study enzyme function and inhibition, particularly kinases and phosphotransferases.
• Ligand Synthesis for Catalysis: The phosphorus center and heterocyclic system can be utilized to develop novel ligands for transition metal catalysis.
• Material Science Research: Potential monomer or additive for creating specialized polymers with unique thermal or electronic properties.

Basic Information

Product Name	(4-Chloro-5-Nitro-2-Pyrimidinylamino)Dichlorophosphine Oxide
CAS No.	6110-60-7
Molecular Formula	C4H3Cl3N4O3P
Molecular Weight	307.42 g/mol
Synonyms	Dichloro[(4-chloro-5-nitro-2-pyrimidinyl)amino]phosphine oxide; (4-Chloro-5-nitro-2-pyrimidinylamino)phosphonic dichloride; 2-Amino-4-chloro-5-nitropyrimidine phosphonic dichloride; N-(4-Chloro-5-nitro-2-pyrimidinyl)phosphoramidic dichloride; Phosphoramidic dichloride, N-(4-chloro-5-nitro-2-pyrimidinyl)-; 6110-60-7; 4-Chloro-5-nitro-2-pyrimidinylaminodichlorophosphine oxide
EINECS	Contact for details

Quality Control

Every batch of (4-Chloro-5-Nitro-2-Pyrimidinylamino)Dichlorophosphine Oxide is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.