Description

(+ -)-Isoproterenol Hemisulfate is a synthetic catecholamine and a non-selective β-adrenergic receptor agonist. This compound is of significant importance as a key pharmaceutical intermediate and reference standard in cardiovascular and respiratory research. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors for drug development and analytical applications.

Application

• Pharmaceutical Intermediate: Critical synthesis component for β-agonist medications.
• Research Chemical: Used as a reference standard in pharmacological studies of adrenergic receptors.
• Cardiovascular Research: Employed in in vitro and in vivo models to study heart rate, contractility, and vasodilation.
• Respiratory Research: Applied in studies investigating bronchial smooth muscle relaxation and asthma.
• Analytical Standard: Serves as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control.
• Biochemical Assays: Utilized in enzyme-linked assays and other test systems to evaluate drug effects and receptor binding.

Basic Information

Product Name	(+ -)-Isoproterenol Hemisulfate
CAS No.	6078-56-4
Molecular Formula	C11H17NO3 · ½H2SO4
Molecular Weight	247.27 (free base) / 278.31 (hemisulfate salt)
Synonyms	Isoprenaline Hemisulfate; DL-Isoproterenol Hemisulfate; (±)-Isoproterenol Hemisulfate; 3,4-Dihydroxy-α-[(isopropylamino)methyl]benzyl Alcohol Hemisulfate; 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol Hemisulfate; Isoproterenol Sulfate; Aleudrin; Aludrin; Isuprel; Norisodrine
EINECS	Contact for details

Quality Control

Our (+ -)-Isoproterenol Hemisulfate is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for research and pharmaceutical use. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and identification is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.