Description

1,3-Dimethyl-2-Dimethylamino-1,3,2-Diazaphospholidine is a versatile and highly reactive organophosphorus compound that serves as a crucial building block in advanced chemical synthesis. Its value lies in its role as a potent phosphitylating and coupling agent, enabling the efficient formation of phosphite and phosphate esters under mild conditions. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for oligonucleotide synthesis and the development of novel catalysts.

Application

• Oligonucleotide Synthesis: A key reagent in the phosphoramidite method for the automated solid-phase synthesis of DNA and RNA strands.
• Phosphite & Phosphate Ester Production: Acts as a precursor for synthesizing complex phosphite and phosphate ligands used in homogeneous catalysis.
• Pharmaceutical Intermediate: Employed in the synthesis of nucleotide analogs and other active pharmaceutical ingredients (APIs) with phosphorus-containing moieties.
• Agrochemical Synthesis: Used in the production of certain herbicides, insecticides, and plant growth regulators that contain phosphorous esters.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating polymers with specific phosphorus-based functional groups.
• Catalyst Ligand Preparation: Facilitates the synthesis of specialized phosphine and phosphite ligands for transition metal catalysts.
• Chemical Research & Development: A valuable tool for exploring new phosphorylation reactions and developing novel synthetic methodologies in academic and industrial R&D labs.

Basic Information

Item	Details
Product Name	1,3-Dimethyl-2-Dimethylamino-1,3,2-Diazaphospholidine
CAS No.	6069-38-1
Molecular Formula	C6H16N3P
Molecular Weight	161.19 g/mol
Synonyms	2-Dimethylamino-1,3-dimethyl-1,3,2-diazaphospholidine; N,N-Dimethyl-P,P-dimethylphosphoramidous diamide cyclic; 1,3-Dimethyl-2-(dimethylamino)-1,3,2-diazaphospholidine; Dimethylamino-dimethyl-diazaphospholidine; Cyclic dimethylphosphoramidous diamide derivative; Phosphoramidite reagent; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-2-Dimethylamino-1,3,2-Diazaphospholidine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames. Due to its reactivity with moisture and air, containers must be kept sealed and handled under anhydrous conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.