Description

Phenacyltriphenylphosphonium Bromide is a versatile and highly reactive Wittig reagent salt, essential for the formation of carbon-carbon double bonds in organic synthesis. Its primary value lies in enabling the efficient synthesis of alkenes, olefins, and other complex organic molecules through the Wittig reaction and related ylide chemistry. This compound is a critical raw material for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where precise olefination is required.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing olefinic bonds in active pharmaceutical ingredients (APIs) and complex drug molecules.
• Agrochemical Production: Used in the synthesis of specific insecticide and herbicide intermediates that require alkene functional groups.
• Fine Chemical & Specialty Chemical Manufacturing: Employed in the production of flavors, fragrances, and performance chemicals via ylide chemistry.
• Academic & Industrial R&D: A staple Wittig reagent in research laboratories for method development and novel compound discovery.
• Material Science: Potential use in synthesizing organic precursors for polymers and advanced organic electronic materials.
• Synthesis of Natural Products & Complex Molecules: Facilitates stereoselective alkene formation in the total synthesis of complex natural products.

Basic Information

Product Name	Phenacyltriphenylphosphonium Bromide
CAS No.	6048-29-9
Molecular Formula	C26H22BrOP
Molecular Weight	461.33 g/mol
Synonyms	(2-Oxo-2-phenylethyl)triphenylphosphonium bromide; 2-Oxo-2-phenylethyltriphenylphosphonium bromide; Phenacyltriphenylphosphonium bromide; Triphenyl(2-oxo-2-phenylethyl)phosphonium bromide; α-Oxobenzyltriphenylphosphonium bromide; (Phenacyl)triphenylphosphonium bromide; Phenylglyoxyltriphenylphosphonium bromide; Wittig reagent salt
EINECS	227-947-1

Quality Control

Our Phenacyltriphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and loss on drying for moisture content, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	228 - 232 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.