Description

tert-Butyl-D9-Amine is a deuterated organic compound where nine hydrogen atoms in the tert-butylamine molecule are replaced by deuterium, a stable isotope of hydrogen. This high isotopic purity makes it an essential tool in advanced analytical chemistry, particularly for use as an internal standard in mass spectrometry to ensure accurate quantification. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and environmental analysis sectors.

Application

• Internal Standard for Mass Spectrometry (MS): Critical for quantitative analysis in LC-MS and GC-MS methods, improving accuracy and reliability in drug metabolism and pharmacokinetics (DMPK) studies.
• Pharmaceutical Research & Development: Used in the synthesis and analysis of deuterated drug candidates for improved metabolic stability and as tracers in mechanistic studies.
• Metabolomics and Biomarker Discovery: Enables precise measurement of amine-containing metabolites in complex biological samples.
• Environmental Analysis: Serves as a reference standard for detecting and quantifying volatile amine pollutants or degradation products.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated reagent or shift reference in nuclear magnetic resonance spectroscopy.
• Chemical Synthesis Intermediate: Used in specialized organic synthesis to introduce a deuterated tert-butylamino group into target molecules.

Basic Information

Product Name	tert-Butyl-D9-Amine
CAS No.	6045-08-5
Molecular Formula	C4D9N
Molecular Weight	80.19 g/mol
Synonyms	2-Amino-2-methylpropane-D9; 2-Methyl-2-propanamine-D9; (Dimethyl-d6)(methyl-d3)amine; t-Butylamine-D9; tert-Butyl-d9-amine; Deuterated tert-Butylamine; t-BuND2; Perdeuterated tert-Butylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl-D9-Amine is produced and tested under strict quality management systems. Each batch is characterized to ensure high chemical and isotopic purity, with key parameters verified by NMR, GC-MS, and IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) detailing assay, isotopic enrichment (typically >98 atom % D), and impurity profiles. Our quality commitment ensures reliability for your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile and alkaline nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to minimize loss and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.