Description

Mutilin is a naturally occurring diterpenoid antibiotic that serves as the core structural framework for important veterinary medicines. Its significance lies in its potent antibacterial activity against Gram-positive organisms, particularly mycoplasmas, making it a critical precursor in pharmaceutical synthesis. This compound is essential for manufacturers in the veterinary pharmaceutical industry developing treatments for respiratory diseases in livestock, as well as for researchers in antimicrobial discovery.

Application

• Veterinary Antibiotic Precursor: Primary use as the key starting material for the semi-synthesis of pleuromutilin-derived antibiotics like tiamulin and valnemulin.
• Animal Health Products: Manufacture of feed additives and injectable solutions for the prevention and treatment of swine dysentery and enzootic pneumonia.
• Antimicrobial Research: Valuable reference standard and lead compound in R&D for novel antibiotics targeting drug-resistant bacterial strains.
• Biochemical Studies: Used in microbiological and pharmacological research to study protein synthesis inhibition and mechanism of action.
• Pharmaceutical Intermediates: Serves as a high-value intermediate in multi-step synthetic routes for advanced pharmaceutical ingredients (APIs).

Basic Information

Product Name	Mutilin
CAS No.	6040-37-5
Molecular Formula	C₂₂H₃₄O₅
Molecular Weight	378.50 g/mol
Synonyms	(+)-Pleuromutilin; Dihydropleuromutilin; NSC 169435; Pleuromutilin; (1S,2R,3S,4S,7R,8R,9S,11S)-4-Hydroxy-3,7,11-trimethyl-8-(2-methyl-1-oxobutoxy)tricyclo[5.4.0.0²,⁹]undecane-1-carboxylic acid; Antibiotic 1067; LE-1067
EINECS	227-933-7

Quality Control

Our Mutilin is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, potency, and impurity profiles. Quality standards are aligned with ICH guidelines for impurities and stability, supporting its use in regulated API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.