Description

1-(2-Thienyl)-3-(4-Chlorophenyl)-2-Propen-1-One is a high-purity organic compound belonging to the class of chalcone derivatives, characterized by its distinct molecular structure incorporating thiophene and chlorophenyl moieties. This compound is valued for its role as a versatile synthetic intermediate and a key scaffold in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in organic synthesis, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in the development of molecules with potential anti-inflammatory, anticancer, or antimicrobial activity.
• Agrochemical Research: Used in the development and optimization of new active ingredients for crop protection products, leveraging its unique heterocyclic structure.
• Organic Synthesis: Acts as a key precursor for complex organic transformations, including cyclization reactions to form heterocyclic compounds like flavones and pyrazolines.
• Material Science: Investigated as a monomer or dopant for the development of advanced organic electronic materials, such as semiconductors or nonlinear optical (NLO) materials.
• Chemical Research & Development: Employed in academic and industrial labs for structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(2-Thienyl)-3-(4-Chlorophenyl)-2-Propen-1-One
CAS No.	6028-96-2
Molecular Formula	C13H9ClOS
Molecular Weight	248.72 g/mol
Synonyms	3-(4-Chlorophenyl)-1-(2-thienyl)-2-propen-1-one; 1-(Thiophen-2-yl)-3-(4-chlorophenyl)prop-2-en-1-one; 2-Propen-1-one, 1-(2-thienyl)-3-(4-chlorophenyl)-; (E)-1-(Thiophen-2-yl)-3-(4-chlorophenyl)prop-2-en-1-one; 4-Chlorochalcone thiophene derivative; TCO; 4'-Chloro-2-thienylchalcone
EINECS	Contact for details

Quality Control

Our 1-(2-Thienyl)-3-(4-Chlorophenyl)-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.