Description

1-Bromo-4-Methylbicyclo[2.2.2]octane is a specialized bicyclic organic bromide, a high-purity building block valued for its rigid, three-dimensional structure. This compound is essential for advanced organic synthesis, particularly in pharmaceutical research and materials science where its unique steric and electronic properties are leveraged. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates requiring complex, bridged ring systems.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides where the bicyclo[2.2.2]octane scaffold can impart favorable biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis and cross-coupling reactions.
• Materials Science Research: Employed in the development of advanced organic materials, such as metal-organic frameworks (MOFs) or liquid crystals, where its shape-persistent core is advantageous.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including radical reactions and transition-metal-catalyzed functionalizations of C-Br bonds.

Basic Information

Product Name	1-Bromo-4-Methylbicyclo[2.2.2]octane
CAS No.	697-40-5
Molecular Formula	C9H15Br
Molecular Weight	203.12 g/mol
Synonyms	4-Methyl-1-bromobicyclo[2.2.2]octane; 1-Bromo-4-methylbicyclo[2.2.2]octane; Bicyclo[2.2.2]octane, 1-bromo-4-methyl-; 4-Methylbicyclo[2.2.2]oct-1-yl bromide
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-4-Methylbicyclo[2.2.2]octane is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.