Description

1-Ethoxy-4,5-Dihydro-1H-Phosphole 1-Oxide is a specialized organophosphorus compound that serves as a versatile building block in advanced chemical synthesis. Its unique heterocyclic structure, featuring a phosphole oxide core, makes it a valuable precursor for developing novel ligands, catalysts, and functional materials. This high-purity intermediate is essential for research and development laboratories, pharmaceutical companies, and agrochemical manufacturers focused on creating innovative products.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting complex molecular scaffolds.
• Ligand Synthesis: Serves as a core structure for developing specialized phosphine-based ligands used in homogeneous catalysis, such as cross-coupling and hydrogenation reactions.
• Agrochemical Research: Employed in the research and development of new generation pesticides and herbicides, where the phosphole moiety can impart unique biological activity.
• Material Science: Used in the synthesis of advanced polymers, flame retardants, and electronic materials that benefit from phosphorus-containing functional groups.
• Organometallic Chemistry: Acts as a starting material for creating metal-organic frameworks (MOFs) and other coordination complexes with tailored properties.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists exploring new reaction methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Ethoxy-4,5-Dihydro-1H-Phosphole 1-Oxide
CAS No.	695-62-5
Molecular Formula	C6H11O2P
Molecular Weight	146.12 g/mol
Synonyms	1-Ethoxy-4,5-dihydrophosphole 1-oxide; 1-Ethoxy-4,5-dihydro-1H-phosphole 1-oxide; 4,5-Dihydro-1-ethoxy-1H-phosphole 1-oxide; Phosphole, 1-ethoxy-4,5-dihydro-, 1-oxide; 1-Ethoxy-3,4-dihydrophosphole 1-oxide (alternative numbering); Ethoxyphospholene oxide
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-4,5-Dihydro-1H-Phosphole 1-Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.