Description

3,3,3-Trifluoropropyl-1-Boronic Acid CAS NO 674-55-5 is a high-value organoboron building block characterized by its trifluoropropyl functional group. This compound is essential for introducing fluorine-containing motifs into target molecules, a critical strategy for modulating their physicochemical and biological properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, such as the Suzuki-Miyaura reaction.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated side chains to enhance metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoropropyl group can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or precursor for creating specialty polymers and advanced materials with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the synthesis of novel boron-containing ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Research: A versatile reagent for academic and industrial R&D focused on exploring new fluorinated chemical spaces and reaction methodologies.
• Liquid Crystal and Electronic Materials: Potential precursor for components in display technologies and organic electronics due to the influence of fluorine on dielectric properties.

Basic Information

Product Name	3,3,3-Trifluoropropyl-1-Boronic Acid
CAS No.	674-55-5
Molecular Formula	C3H6BF3O2
Molecular Weight	129.89 g/mol
Synonyms	(3,3,3-Trifluoropropyl)boronic Acid; 3,3,3-Trifluoropropan-1-boronic Acid; 3,3,3-Trifluoropropylboronic Acid; B-(3,3,3-Trifluoropropyl)boronic Acid; 3,3,3-Trifluoro-1-propaneboronic Acid; 674-55-5; Trifluoropropylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 3,3,3-Trifluoropropyl-1-Boronic Acid is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.