Description

1-Chloro-1,2,2-trifluorocyclobutane is a halogenated cyclobutane derivative of significant industrial interest. This compound serves as a versatile intermediate and specialty solvent, valued for its unique combination of volatility and chemical stability. It is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking high-purity fluorinated building blocks.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon in the synthesis of active pharmaceutical ingredients (APIs), leveraging the trifluoromethyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Specialty Solvent: Functions as a highly volatile and effective solvent for reactions involving strong acids or organic substrates, particularly in niche extraction and purification processes.
• Refrigerant & Propellant Formulation: A potential component in next-generation, low-global-warming-potential (GWP) blends for refrigeration and aerosol applications.
• Polymer & Material Science: Acts as a monomer or modifying agent in the synthesis of fluoropolymers and specialty coatings with enhanced chemical resistance.
• Electronics Manufacturing: Employed in precision cleaning and as a carrier fluid in the deposition of thin films for semiconductor fabrication.

Basic Information

Product Name	1-Chloro-1,2,2-Trifluorocyclobutane
CAS No.	661-71-2
Molecular Formula	C4H4ClF3
Molecular Weight	144.52 g/mol
Synonyms	1-Chloro-1,2,2-trifluorocyclobutane; Cyclobutane, 1-chloro-1,2,2-trifluoro-; 1,2,2-Trifluoro-1-chlorocyclobutane; Chlorotrifluorocyclobutane; CTFCB; Freon 254cb (related series); HCFC-254cb (potential designation); R-254cb
EINECS	Contact for details

Quality Control

Our 1-Chloro-1,2,2-trifluorocyclobutane is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are properly sealed. Recommended storage temperature is 2-8°C to minimize volatility and maintain stability for extended periods.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.05%
Acidity (as HCl)	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.