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Dichloromethyl[3-(2,2,2-Trifluoroethoxy)Propyl]Silane CAS NO 660-23-1


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CAS No.:660-23-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloromethyl[3-(2,2,2-Trifluoroethoxy)Propyl]Silane is a specialized organosilicon compound featuring a reactive dichloromethylsilane group linked to a trifluoroethoxypropyl chain. This unique structure makes it a valuable high-purity intermediate for synthesizing advanced silicone polymers and surface-modifying agents. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating products with tailored surface properties and chemical resistance.

Application

  • Key Intermediate in Pharmaceutical Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) and prodrugs, particularly where fluorinated side chains are required for metabolic stability or bioavailability.
  • Surface Modification Agent: Imparts hydrophobic and oleophobic properties to glass, silica, metals, and polymers, enhancing water and stain resistance.
  • Precursor for Silicone Resins & Elastomers: Serves as a building block for synthesizing specialty fluorosilicones with enhanced solvent, fuel, and chemical resistance for demanding automotive, aerospace, and industrial applications.
  • Adhesion Promoter in Coatings & Sealants: Improves the bonding of coatings, adhesives, and sealants to difficult substrates, including fluoropolymers and metals.
  • Research & Development (R&D): Employed in academic and industrial labs for developing novel materials, including liquid crystals, organic semiconductors, and advanced composites.
  • Agrochemical Formulations: Used in the synthesis of surfactants and adjuvants that improve the efficacy and rainfastness of pesticide formulations.

Basic Information

Product Name Dichloromethyl[3-(2,2,2-Trifluoroethoxy)Propyl]Silane
CAS No. 660-23-1
Molecular Formula C7H11Cl2F3OSi
Molecular Weight 267.15 g/mol
Synonyms Methyldichloro[3-(2,2,2-trifluoroethoxy)propyl]silane; 3-(2,2,2-Trifluoroethoxy)propyldichloromethylsilane; (3-(2,2,2-Trifluoroethoxy)propyl)methyldichlorosilane; Dichloromethyl(3-(2,2,2-trifluoroethoxy)propyl)silane; Silane, dichloromethyl[3-(2,2,2-trifluoroethoxy)propyl]-; Methyl[3-(2,2,2-trifluoroethoxy)propyl]dichlorosilane
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Quality Control

Our production of Dichloromethyl[3-(2,2,2-Trifluoroethoxy)Propyl]Silane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is analyzed using advanced techniques including GC, NMR, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ISO 9001 quality management standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item Specification
Appearance Clear, colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Water Content (Karl Fischer) ≤ 0.1%
Density (at 20°C) ~1.25 g/cm³
Refractive Index (n20D) ~1.395

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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