Description

Propargyl Iodide is a versatile and highly reactive organic halide compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the propargyl and iodide functional groups, enabling efficient carbon-carbon and carbon-heteroatom bond formation. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular architectures for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the construction of nitrogen-containing heterocycles and other complex bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactivity for structural diversification.
• Material Science: Acts as a precursor for functionalized polymers and dendrimers with tailored properties.
• Cross-Coupling Reactions: Serves as an effective electrophile in palladium-catalyzed Sonogashira and other cross-coupling reactions.
• Alkynylation Agent: Employed to introduce propargyl groups into various substrates under mild conditions.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for methodology development and library synthesis.

Basic Information

Product Name	Propargyl Iodide
CAS No.	659-86-9
Molecular Formula	C3H3I
Molecular Weight	165.96 g/mol
Synonyms	3-Iodo-1-propyne; 3-Iodopropyne; Iodomethylacetylene; 1-Iodo-2-propyne; Propargyl iodide; HC≡CCH2I
EINECS	211-533-8

Quality Control

Our Propargyl Iodide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay by GC or HPLC and identity confirmation by FT-IR and NMR spectroscopy, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and volatility. Due to its light-sensitive and highly volatile nature, containers should be kept sealed and allowed to equilibrate to room temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.