Description

Chlorodiiodomethane is a versatile halogenated methane derivative with the CAS registry number 638-73-3. This compound serves as a valuable synthetic intermediate, particularly in the construction of complex organic molecules and in materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for advanced synthesis and methodological studies.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring halogenated scaffolds.
• Agrochemical Synthesis: Serves as a key building block for creating advanced pesticides, herbicides, and fungicides with specific activity profiles.
• Organic Synthesis Reagent: Employed in laboratories as a reagent for introducing diiodomethyl or chloroiodomethyl groups via various coupling and substitution reactions.
• Materials Science Research: Investigated for the development of novel polymers, liquid crystals, and organic electronic materials due to its unique halogen content.
• Cross-Coupling Reactions: Acts as a substrate or reagent in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	Chlorodiiodomethane
CAS No.	638-73-3
Molecular Formula	CHClI2
Molecular Weight	296.28 g/mol
Synonyms	Dichloroiodomethane (common misnomer); Methane, chlorodiiodo-; Chlorodiiodomethane; Dichloroiodomethane (incorrect but used); Iodochlorodiiodomethane (alternate); Halon; CHClI2; Diiodochloromethane
EINECS	211-357-6

Quality Control

Our Chlorodiiodomethane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by GC or HPLC), identity confirmation (by FT-IR and NMR), and levels of specific impurities. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C (refrigerated) for long-term stability. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Clear, yellow to amber liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.