Description

1-Chloro-2-Iodoethane is a versatile halogenated alkane building block of significant interest in synthetic organic chemistry. Its bifunctional nature, featuring both chlorine and iodine substituents, makes it a valuable reagent for selective substitution and cyclization reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides through alkylation and cross-coupling reactions.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions (SN2) where the iodine acts as a superior leaving group, enabling efficient functional group transformations.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for methodology development and exploring new reaction pathways.
• Ligand and Catalyst Preparation: Utilized in the synthesis of organometallic complexes and specialized ligands for catalytic applications.

Basic Information

Product Name	1-Chloro-2-Iodoethane
CAS No.	624-70-4
Molecular Formula	C2H4ClI
Molecular Weight	190.41 g/mol
Synonyms	Chloroiodoethane; Ethane, 1-chloro-2-iodo-; 2-Chloroethyl iodide; 2-Iodoethyl chloride; β-Chloroethyl iodide; 1-Iodo-2-chloroethane; (2-Chloroethyl)iodide; NSC 60545
EINECS	210-860-5

Quality Control

Our 1-Chloro-2-Iodoethane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reactive metals. Recommended storage temperature is 2-8°C to maximize stability. Keep container tightly sealed when not in use to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	2.10 - 2.20 g/mL
Refractive Index (n20D)	1.580 - 1.590
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.