Description

1-Propyn-1-Yl Iodide is a versatile and reactive organoiodine compound, serving as a crucial building block in advanced organic synthesis. Its value lies in its ability to act as a propiolate equivalent and a source of the propynyl group, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with acetylene functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkyne-based structures.
• Material Science Research: Employed in the synthesis of novel polymers, liquid crystals, and organic electronic materials where conjugated systems are critical.
• Cross-Coupling Reactions: A valuable substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Organic Synthesis Reagent: Functions as an electrophilic alkynylation agent in the synthesis of natural products, fine chemicals, and complex organic molecules.
• Ligand & Catalyst Preparation: Used in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	1-Propyn-1-Yl Iodide
CAS No.	624-66-8
Molecular Formula	C3H3I
Molecular Weight	165.96 g/mol
Synonyms	Iodoacetylene; Iodoethyne; Ethynyl iodide; Propiolyl iodide; Acetylene, iodo-; 1-Iodopropyne; 1-Iodo-1-propyne; 1-Propynyl iodide
EINECS	210-854-7

Quality Control

Our 1-Propyn-1-Yl Iodide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated place. Recommended storage temperature is 2-8°C to minimize decomposition and maintain stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizers and bases.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.