Description

2-Thiophenamine CAS NO 616-46-6 is a versatile heterocyclic aromatic amine, serving as a critical building block in advanced organic synthesis. Its unique thiophene-based structure makes it an essential precursor for creating complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the thiophene ring contributes to biological activity and selectivity.
• Material Science & Organic Electronics: Acts as a precursor for conductive polymers, organic semiconductors, and non-linear optical (NLO) materials due to its electron-rich heterocyclic system.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments, where it imparts specific color properties and stability.
• Ligand & Catalyst Development: Useful in organometallic chemistry for creating novel ligands and catalysts used in cross-coupling and other catalytic reactions.
• Research & Development: Serves as a fundamental reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Thiophenamine
CAS No.	616-46-6
Molecular Formula	C4H5NS
Molecular Weight	99.15 g/mol
Synonyms	2-Aminothiophene; Thiophen-2-ylamine; 2-Thienylamine; 2-Thiopheneamine; USAF EK-1719; 2-Thienamine; NSC 403697; 2-Thiophenamine
EINECS	210-482-8

Quality Control

Our 2-Thiophenamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown liquid or crystalline mass
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.