Description

1-Iodo-2-Methylbutane is a valuable halogenated organic building block, specifically a secondary alkyl iodide. This compound is prized for its reactivity in carbon-carbon bond formation, making it a critical intermediate in advanced synthetic chemistry. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) via alkylation and cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a precursor for modifying polymers and creating functionalized materials.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and metal-catalyzed coupling reactions (e.g., Negishi, Kumada) to introduce the 2-methylbutyl moiety.
• Chemical Research & Development: Essential for method development and scale-up processes in fine chemical manufacturing.
• Ligand and Catalyst Preparation: Used in the synthesis of specialized ligands for catalytic systems.

Basic Information

Product Name	1-Iodo-2-Methylbutane
CAS No.	616-14-8
Molecular Formula	C5H11I
Molecular Weight	198.05 g/mol
Synonyms	2-Methylbutyl Iodide; Isoamyl Iodide; (2-Methylbutyl)iodide; 1-Iodo-2-methylbutane; sec-Butylcarbinyl Iodide
EINECS	210-476-4

Quality Control

Our 1-Iodo-2-Methylbutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Specific Gravity (20°C)	1.50 - 1.55
Refractive Index (n20D)	1.490 - 1.495

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.