Description

2-Nitrothiophene is a versatile nitro-substituted heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This intermediate is particularly sought after by research and development teams in the pharmaceutical and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the thiophene scaffold for enhanced biological activity.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers, organic semiconductors, and other functional materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and organic pigments.
• Research & Development: Employed in academic and industrial R&D for method development and the exploration of new chemical entities.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2-Nitrothiophene
CAS No.	609-45-0
Molecular Formula	C4H3NO2S
Molecular Weight	129.14 g/mol
Synonyms	2-Nitrothiophene; Thiophene, 2-nitro-; Nitrothiophene; 2-Nitro-thiophene; 2-Thienylnitromethane; NSC 403697; 2-Nitro-thiophen; 2-Nitro-thiofene
EINECS	210-200-8

Quality Control

Our 2-Nitrothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	42 - 46 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.