Description

5-Nitroisoquinoline is a versatile nitro-substituted heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the reactivity of the nitro group and the isoquinoline scaffold, enabling the construction of complex molecules for pharmaceutical and material science applications. This high-purity building block is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various bioactive molecules, including potential kinase inhibitors, antimicrobial agents, and other nitrogen-containing heterocycles.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its structural motif for biological activity.
• Dye and Pigment Synthesis: Serves as a starting material for creating nitro- and amino-substituted dyes and functional colorants.
• Material Science: Building block for organic ligands in catalysis and for the preparation of advanced organic electronic materials.
• Chemical Research: A valuable reagent for method development in organic synthesis, particularly in nitration and reduction studies or heterocyclic chemistry.

Basic Information

Product Name	5-Nitroisoquinoline
CAS No.	607-32-9
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	Isoquinoline, 5-nitro-; 5-Nitro-isoquinoline; Nitroisoquinoline; 5-Nitroisoquinolin; 5-Nitro-1-azanaphthalene; 5-Nitro-2-azanaphthalene; 5-NIQL; 607-32-9
EINECS	210-141-1

Quality Control

Our 5-Nitroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.