Description

Proxyphylline is a xanthine derivative pharmaceutical intermediate and active ingredient known for its bronchodilator properties. It is a critical compound for the development and production of respiratory medications, offering a key building block for therapeutic formulations. This product is essential for pharmaceutical manufacturers, research institutions, and chemical suppliers serving the global healthcare sector.

Application

• Pharmaceutical Active Ingredient (API): Primary use as a bronchodilator in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the manufacture of more complex therapeutic agents within the xanthine class.
• Research & Development: Utilized in biochemical and pharmacological research to study airway smooth muscle relaxation and phosphodiesterase inhibition.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Formulation Development: Used in the development of various dosage forms, including tablets, capsules, and injectables.

Basic Information

Product Name	Proxyphylline
CAS No.	603-00-9
Molecular Formula	C₁₀H₁₄N₄O₃
Molecular Weight	238.24 g/mol
Synonyms	7-(2-Hydroxypropyl)theophylline; Proxyphyllinum; Brontyl; Purophyllin; Spasmolysin; Theo-Propyl; 1,3-Dimethyl-7-(2-hydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione; 3,7-Dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-1H-purine-2,6-dione
EINECS	210-036-7

Quality Control

Our Proxyphylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.