Description

Morphine Sulfate Narcotic Analgesic is the sulfate salt of morphine, a principal alkaloid of opium, widely recognized for its potent analgesic properties. This compound is a critical active pharmaceutical ingredient (API) for the management of severe acute and chronic pain where other treatment options are inadequate. It is essential for pharmaceutical manufacturers developing controlled-release formulations, injectable solutions, and oral tablets. Global supply chains rely on consistent, high-purity morphine sulfate to meet stringent pharmacopeial standards for narcotic analgesic production.

Application

• Pharmaceutical API: Primary ingredient in the formulation of potent analgesic medications for severe pain management.
• Hospital & Clinical Use: Manufacture of injectable solutions for post-operative pain, cancer-related pain, and myocardial infarction.
• Controlled-Release Formulations: Key component in extended-release tablets and capsules for chronic pain conditions.
• Palliative & Hospice Care: Essential for producing medications that alleviate pain and improve quality of life in terminal care.
• Reference Standard: Serves as a certified reference material (CRM) for analytical testing and quality control in laboratories.
• Veterinary Medicine: Used in controlled veterinary applications for severe pain relief in animals.

Basic Information

Product Name	Morphine Sulfate Narcotic Analgesic
CAS No.	64-31-3
Molecular Formula	C17H19NO3 · H2SO4 · 5H2O
Molecular Weight	758.83 g/mol (pentahydrate)
Synonyms	Morphine Sulphate; Morphine Sulfate Pentahydrate; Morphine Hydrogen Sulfate; (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol sulfate (2:1) (salt) pentahydrate; Morphinium Sulfate; Duromorph; MS Contin; Oramorph SR; Morpine
EINECS	200-593-4

Quality Control

Our Morphine Sulfate is manufactured and tested to meet the highest pharmacopeial standards, including USP-NF and European Pharmacopoeia (Ph. Eur.) monographs. Every batch undergoes rigorous analytical testing for identity, potency, and purity, with strict controls for related substances and residual solvents. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results against specification. Our quality system is designed to ensure full traceability and compliance with cGMP guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, 15°C to 25°C (59°F to 77°F). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White, crystalline powder or small crystals
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (Anhydrous Basis)	98.0% - 102.0%
pH (5% Solution)	4.0 - 6.0
Loss on Drying	10.0% - 13.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfate Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.