Description

Salbutamolhemisulphate is the hemisulfate salt form of the widely used β-2 adrenergic receptor agonist, Salbutamol. This compound is a key active pharmaceutical ingredient (API) and intermediate, valued for its enhanced stability and solubility profile compared to the free base. It is essential for manufacturers in the pharmaceutical industry requiring a reliable and high-purity source for formulating respiratory medications. The product is supplied under stringent quality controls to meet the exacting standards of global regulatory frameworks.

Application

• Primary Active Pharmaceutical Ingredient (API): Core component in the manufacture of bronchodilator medications for treating asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions.
• Formulation of Metered-Dose Inhalers (MDIs): Used in pressurized inhalation aerosols for rapid relief of bronchospasm.
• Dry Powder Inhaler (DPI) Formulations: Integral to the production of breath-activated powdered inhalers.
• Nebulizer Solution Production: Serves as the active agent in liquid formulations for use in nebulizer machines.
• Pharmaceutical Research & Development: Employed as a critical reference standard and intermediate in the synthesis of novel therapeutic agents.
• Veterinary Pharmaceuticals: Used in medications for managing respiratory distress in animals.

Basic Information

Product Name	Salbutamolhemisulphate
CAS No.	5111022-70-9
Molecular Formula	C26H44N2O10S
Molecular Weight	576.70 g/mol
Synonyms	Albuterol Hemisulfate; Salbutamol Hemisulfate; (±)-α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α'-diol hemisulfate; 2-(tert-Butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol hemisulfate; Ventolin Hemisulfate; AH-3365 Hemisulfate; Proventil Hemisulfate
EINECS	Contact for details

Quality Control

Our Salbutamolhemisulphate is manufactured and tested under a quality management system designed to meet the stringent requirements of the global pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure compliance with relevant pharmacopoeial standards (e.g., USP, EP, BP). A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and ensure stability.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.