Description

5-(4-Trifluoromethoxyphenyl)-1H-Indole is a high-value, multi-functional indole derivative characterized by its trifluoromethoxy-substituted phenyl ring. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the indole scaffold and the metabolic stability imparted by the trifluoromethoxy group.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to construct complex heterocyclic systems for material and medicinal chemistry.
• Material Science: Investigated as a monomer or functional component in the creation of specialty polymers and organic electronic materials due to its unique electronic properties.
• Biochemical Tool Compound: Serves as a research chemical in biochemical assays and as a probe for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	5-(4-Trifluoromethoxyphenyl)-1H-Indole
CAS No.	599198-16-0
Molecular Formula	C15H10F3NO
Molecular Weight	277.24 g/mol
Synonyms	5-[4-(Trifluoromethoxy)phenyl]-1H-indole; 1H-Indole, 5-[4-(trifluoromethoxy)phenyl]-; 5-(4-Trifluoromethoxyphenyl)indole; 5-(p-Trifluoromethoxyphenyl)indole; 4-(1H-Indol-5-yl)phenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 5-(4-Trifluoromethoxyphenyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.