Description

Ethanone, 1-[(2R,5S)-2-Ethoxy-2,5-Dihydro-5-Methyl-2-Oxido-1,2-Oxaphosphol-3-Yl]-, Rel- (9Ci) CAS NO 599179-49-4 is a high-purity, stereochemically defined organophosphorus compound. This specialty chemical serves as a critical chiral building block and intermediate in advanced synthetic chemistry, enabling the production of complex molecules with high enantiomeric purity. It is essential for research and development laboratories and industrial-scale manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Catalyst & Ligand Precursor: Serves as a precursor for the development of novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Investigated as a monomer or functional additive in the development of specialty polymers and materials with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities, government labs, and corporate R&D centers exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	Ethanone, 1-[(2R,5S)-2-Ethoxy-2,5-Dihydro-5-Methyl-2-Oxido-1,2-Oxaphosphol-3-Yl]-, Rel- (9Ci)
CAS No.	599179-49-4
Molecular Formula	C8H13O5P
Molecular Weight	220.16 g/mol
Synonyms	rel-(2R,5S)-2-Ethoxy-5-methyl-2-oxido-2,5-dihydro-1,2-oxaphosphol-3-yl ethanone; (2R,5S)-2-Ethoxy-5-methyl-2-oxido-2,5-dihydro-1,2-oxaphosphol-3-yl methyl ketone; 1-[(2R,5S)-2-Ethoxy-2,5-dihydro-5-methyl-2-oxido-1,2-oxaphosphol-3-yl]ethanone; 599179-49-4; Chiral oxaphospholane derivative; Ethoxy-methyl-oxaphospholane ethanone.
EINECS	Contact for details

Quality Control

Our production of this high-value chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric excess. Each lot undergoes comprehensive analysis including Chiral HPLC for enantiopurity verification, NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.