Description

(S)-3-Cyclopentyl-2-(4-Methanesulfonyl-Phenyl)-n-Thiazol-2-Yl-Propionamide is a high-purity, non-racemic chiral compound featuring a cyclopentyl group, a methanesulfonylphenyl moiety, and a thiazole-linked propionamide structure. This molecule is of significant value as a sophisticated pharmaceutical intermediate or research chemical for the development of novel bioactive agents. It is primarily utilized by pharmaceutical R&D organizations and contract research and manufacturing (CRO/CMO) companies engaged in drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly for small molecule therapeutics.
• Protease Inhibitor Research: The structural motifs suggest potential application in the development of inhibitors for specific enzyme targets.
• Kinase Inhibitor Scaffold: Serves as a core structure for designing and optimizing novel kinase inhibitors in oncology and inflammatory disease research.
• Chemical Biology Probes: Used to create tool compounds for studying biological pathways and target validation in academic and industrial research.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a chiral synthon to introduce stereochemical complexity in multi-step synthetic sequences.

Basic Information

Product Name	(S)-3-Cyclopentyl-2-(4-Methanesulfonyl-Phenyl)-n-Thiazol-2-Yl-Propionamide
CAS No.	599164-57-5
Molecular Formula	C18H22N2O3S2
Molecular Weight	378.51 g/mol
Synonyms	(S)-3-Cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide; 2-(4-Methanesulfonylphenyl)-3-cyclopentyl-N-(thiazol-2-yl)propionamide, (S)-; (S)-3-Cyclopentyl-2-(4-(methylsulfonyl)phenyl)-N-(thiazol-2-yl)propanamide; (S)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-(1,3-thiazol-2-yl)propanamide; (2S)-3-Cyclopentyl-2-[4-(methylsulfonyl)phenyl]-N-(1,3-thiazol-2-yl)propanamide; CAS 599164-57-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC for purity, chiral HPLC for enantiomeric excess, and spectroscopic confirmation (NMR, MS). Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.