Description

1H-Indole-1-Carboxylic Acid, 7-(Cyanomethyl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex heterocyclic compounds due to its reactive ester and nitrile functional groups.
• Agrochemical Development: Potential application in the research and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 7-(Cyanomethyl)-, 1,1-Dimethylethyl Ester
CAS No.	597544-18-8
Molecular Formula	C16H18N2O2
Molecular Weight	270.33 g/mol
Synonyms	tert-Butyl 7-(cyanomethyl)-1H-indole-1-carboxylate; 7-(Cyanomethyl)-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-7-(cyanomethyl)indole; 7-Cyanomethyl-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; BOC-7-Cyanomethylindole; tert-Butyl 7-(cyanomethyl)indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 7-(Cyanomethyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.