Description

4-tert-Butyl-4'-Fluorobenzhydrol is a specialized fluorinated benzhydrol derivative, serving as a crucial chiral intermediate and building block in advanced organic synthesis. Its molecular structure, featuring both a tert-butyl group and a fluorine atom, makes it valuable for modulating the steric and electronic properties of target compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in the design of chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorinated and bulky side groups into specialty polymers, improving their thermal and chemical resistance.
• Chemical Research: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	4-tert-Butyl-4'-Fluorobenzhydrol
CAS No.	596812-34-9
Molecular Formula	C₁₇H₁₉FO
Molecular Weight	258.33 g/mol
Synonyms	4-(1,1-Dimethylethyl)-α-(4-fluorophenyl)benzenemethanol; (4-tert-Butylphenyl)(4-fluorophenyl)methanol; α-(4-tert-Butylphenyl)-4-fluorobenzyl alcohol; 1-(4-tert-Butylphenyl)-1-(4-fluorophenyl)methanol; Benzhydrol, 4-tert-butyl-4'-fluoro-; 4'-Fluoro-4-tert-butylbenzhydrol; p-tert-Butyl-p'-fluorobenzhydrol
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-4'-Fluorobenzhydrol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for sensitive pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.